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A METAL SWITCH FOR CONTROLLING THE ACTIVITY OF MOLECULAR MOTOR PROTEINS
Kinesins are molecular motors that require a divalent metal ion (e.g., Mg(2+)) to convert the energy of ATP hydrolysis into directed force production along microtubules. Here we present the crystal structure of a recombinant kinesin motor domain bound to Mn(2+) and ADP, and report on a serine to cys...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252401/ https://ncbi.nlm.nih.gov/pubmed/22198464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2190 |
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