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Transgenic overexpression of bone morphogenetic protein 11 propeptide in skeleton enhances bone formation
Bone morphogenetic protein 11 (BMP11) is a key regulatory protein in skeletal development. BMP11 propeptide has been shown to antagonize GDF11 activity in vitro. To explore the role of BMP11 propeptide in skeletal formation in vivo, we generated transgenic mice with skeleton-specific overexpression...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252393/ https://ncbi.nlm.nih.gov/pubmed/22093826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.11.019 |
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