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Pharmaceutical regulation of telomerase and its clinical potential

Telomeres serve the dual function of protecting chromosomes from genomic instability as well as protecting the ends of chromosomes from DNA damage machinery. The enzyme responsible for telomere maintenance is telomerase, an enzyme capable of reverse transcription. Telomerase activity is typically li...

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Autors principals: Sprouse, Alyssa A, Steding, Catherine E, Herbert, Brittney-Shea
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251731/
https://ncbi.nlm.nih.gov/pubmed/21973217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01460.x
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