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Pharmaceutical regulation of telomerase and its clinical potential

Telomeres serve the dual function of protecting chromosomes from genomic instability as well as protecting the ends of chromosomes from DNA damage machinery. The enzyme responsible for telomere maintenance is telomerase, an enzyme capable of reverse transcription. Telomerase activity is typically li...

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Dettagli Bibliografici
Autori principali: Sprouse, Alyssa A, Steding, Catherine E, Herbert, Brittney-Shea
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251731/
https://ncbi.nlm.nih.gov/pubmed/21973217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01460.x
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