Metastasis suppressor NM23-H1 promotes repair of UV-induced DNA damage and suppresses UV-induced melanomagenesis

Reduced expression of the metastasis suppressor NM23-H1 is associated with aggressive forms of multiple cancers. Here, we establish that NM23-H1 (termed H1 isoform in human, M1 in mouse) and two of its attendant enzymatic activities, the 3′-5′ exonuclease and nucleoside diphosphate kinase, are novel...

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主要な著者: Jarrett, Stuart G., Novak, Marian, Dabernat, Sandrine, Daniel, Jean-Yves, Mellon, Isabel, Zhang, Qingbei, Harris, Nathan, Ciesielski, Michael J., Fenstermaker, Robert A., Kovacic, Diane, Slominski, Andrzej, kaetzel, David M.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251703/
https://ncbi.nlm.nih.gov/pubmed/22080566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1795
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