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Structural characterization of human Uch37.

Uch37 is a de-ubiquitylating enzyme that is functionally linked with the 26S proteasome via Rpn13, and is essential for metazoan development. Here, we report the X-ray crystal structure of full-length human Uch37 at 2.95 Å resolution. Uch37's catalytic domain is similar to those of all UCH enzy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Burgie, E. Sethe, Bingman, Craig A., Soni, Ameet B., Phillips, George N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251636/
https://ncbi.nlm.nih.gov/pubmed/21953935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23147
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