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The relationship between the binding to and permeabilization of phospholipid bilayer membranes by GS14dK(4), a designed analog of the antimicrobial peptide gramicidin S
The cationic β-sheet cyclic tetradecapeptide cyclo[VKLdKVdYPLKVKLdYP] (GS14dK(4)) is a diastereomeric lysine ring-size analog of the potent naturally occurring antimicrobial peptide gramicidin S (GS) which exhibits enhanced antimicrobial but markedly reduced hemolytic activity compared to GS itself....
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251618/ https://ncbi.nlm.nih.gov/pubmed/17686454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2007.06.023 |
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