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Development of an Effective Therapy for CML

Targeted small molecule drugs have revolutionized treatment of chronic myeloid leukemia (CML) over the last decade. These agents interrupt a constitutively active BCR-ABL, the causative agent for CML, by interfering with ATP-dependent ABL tyrosine kinase. Although the efficacy of tyrosine kinase inh...

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Detalhes bibliográficos
Main Authors: Woessner, David W., Lim, Carol S., Deininger, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251313/
https://ncbi.nlm.nih.gov/pubmed/22157291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0b013e318237e5b7
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