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Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human

Histone H3 lysine 4 (H3K4) methylation is catalyzed by the highly evolutionarily conserved multiprotein complex known as Set1/COMPASS or MLL/COMPASS-like complexes from yeast to human, respectively. Here we have reconstituted fully functional yeast Set1/COMPASS and human MLL/COMPASS-like complex in...

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Autores principales: Takahashi, Yoh-hei, Westfield, Gerwin H., Oleskie, Austin N., Trievel, Raymond C., Shilatifard, Ali, Skiniotis, Georgios
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251153/
https://ncbi.nlm.nih.gov/pubmed/22158900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109360108
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