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Energy landscape of the reactions governing the Na(+) deeply occluded state of the Na(+)/K(+)-ATPase in the giant axon of the Humboldt squid
The Na(+)/K(+) pump is a nearly ubiquitous membrane protein in animal cells that uses the free energy of ATP hydrolysis to alternatively export 3Na(+) from the cell and import 2K(+) per cycle. This exchange of ions produces a steady-state outwardly directed current, which is proportional in magnitud...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251152/ https://ncbi.nlm.nih.gov/pubmed/22143771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116439108 |
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