Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant

No countermeasures currently exist for the prevention or treatment of the severe sequelae of Filovirus (such as Ebola virus; EBOV) infection. To overcome this limitation in our biodefense preparedness, we have designed monoclonal antibodies (mAbs) which could be used in humans as immunoprotectants f...

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Bibliografiske detaljer
Main Authors: Zeitlin, Larry, Pettitt, James, Scully, Corinne, Bohorova, Natasha, Kim, Do, Pauly, Michael, Hiatt, Andrew, Ngo, Long, Steinkellner, Herta, Whaley, Kevin J., Olinger, Gene G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251097/
https://ncbi.nlm.nih.gov/pubmed/22143789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108360108
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