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Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of their agonist-bound conformation

Pyrabactin resistance (PYR) 1 and its relatives belong to a family of soluble abscisic acid (ABA) receptors that inhibit type 2C protein phosphatases (PP2C) when in their agonist-stabilized conformation. Given their switch-like properties, we envisioned that mutations that stabilize their agonist-bo...

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Bibliografiska uppgifter
Huvudupphovsmän: Mosquna, Assaf, Peterson, Francis C., Park, Sang-Youl, Lozano-Juste, Jorge, Volkman, Brian F., Cutler, Sean R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251050/
https://ncbi.nlm.nih.gov/pubmed/22139369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112838108
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