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Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment
BACKGROUND: Sensitive antibody-based tumor targeting has the potential not only to image metastatic and micrometastatic disease, but also to be the basis of targeted therapy. The vast majority of pancreas cancers express carcinoembryonic antigen (CEA). Thus, we sought to evaluate the potential of CE...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251041/ https://ncbi.nlm.nih.gov/pubmed/22214289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-1-24 |
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