Solulin reduces infarct volume and regulates gene-expression in transient middle cerebral artery occlusion in rats

BACKGROUND: Thrombolysis after acute ischemic stroke has only proven to be beneficial in a subset of patients. The soluble recombinant analogue of human thrombomodulin, Solulin, was studied in an in vivo rat model of acute ischemic stroke. METHODS: Male SD rats were subjected to 2 hrs of transient m...

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Bibliografiset tiedot
Päätekijät: Ryang, Yu-Mi, Dang, Jon, Kipp, Markus, Petersen, Karl-Uwe, Fahlenkamp, Astrid V, Gempt, Jens, Wesp, Dominik, Rossaint, Rolf, Beyer, Cordian, Coburn, Mark
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2011
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251036/
https://ncbi.nlm.nih.gov/pubmed/22082476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-113
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