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Ethanol Inhibition of Constitutively Open N-Methyl-d-Aspartate Receptors

N-Methyl-d-aspartate (NMDA) receptors gate a slow and calcium-rich component of the postsynaptic glutamate response. Like all ionotropic glutamate receptors, NMDA subunits contain a highly conserved motif (SYTANLAAF) in the transmembrane (TM) 3 domain that is critically involved in channel gating. M...

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Detalles Bibliográficos
Main Authors: Xu, Minfu, Smothers, C. Thetford, Trudell, James, Woodward, John J.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251024/
https://ncbi.nlm.nih.gov/pubmed/22005043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.187179
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