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Rapid and reproducible single-stage phosphopeptide enrichment of complex peptide mixtures: Application to general and phosphotyrosine-specific phosphoproteomics experiments

Reversible protein phosphorylation is an essential regulatory component of virtually every cellular process, and is frequently dysregulated in cancer. However, significant analytical barriers persist that hamper the routine application of phosphoproteomics in translational settings. Here, we present...

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Autors principals: Kettenbach, Arminja N., Gerber, Scott A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251014/
https://ncbi.nlm.nih.gov/pubmed/21899308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201894j
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