Extraction and inhibition of enzymatic activity of botulinum neurotoxins /B1, /B2, /B3, /B4, and /B5 by a panel of monoclonal anti-BoNT/B antibodies

BACKGROUND: Botulism is caused by botulinum neurotoxins (BoNTs), extremely toxic proteins which can induce respiratory failure leading to long-term intensive care or death. Treatment for botulism includes administration of antitoxins, which must be administered early in the course of the intoxicatio...

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Autors principals: Kalb, Suzanne R, Santana, Wanda I, Geren, Isin N, Garcia-Rodriguez, Consuelo, Lou, Jianlong, Smith, Theresa J, Marks, James D, Smith, Leonard A, Pirkle, James L, Barr, John R
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250939/
https://ncbi.nlm.nih.gov/pubmed/22085466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-12-58
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