Extraction of BoNT/A, /B, /E, and /F with a Single, High Affinity Monoclonal Antibody for Detection of Botulinum Neurotoxin by Endopep-MS

Botulinum neurotoxins (BoNTs) are extremely potent toxins that are capable of causing respiratory failure leading to long-term intensive care or death. The best treatment for botulism includes serotype-specific antitoxins, which are most effective when administered early in the course of the intoxic...

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Autors principals: Kalb, Suzanne R., Garcia-Rodriguez, Consuelo, Lou, Jianlong, Baudys, Jakub, Smith, Theresa J., Marks, James D., Smith, Leonard A., Pirkle, James L., Barr, John R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923190/
https://ncbi.nlm.nih.gov/pubmed/20808925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012237
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