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Pre-Clinical Assessment of (177)Lu-Labeled Trastuzumab Targeting HER2 for Treatment and Management of Cancer Patients with Disseminated Intraperitoneal Disease

Studies from this laboratory have demonstrated the potential of targeting HER2 for therapeutic and imaging applications with medically relevant radionuclides. To expand the repertoire of trastuzumab as a radioimmunoconjugate (RIC) vector, use of (177)Lu was investigated. The combination of a 6.7 d h...

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Библиографические подробности
Главные авторы: Ray, Geoffrey L., Baidoo, Kwamena E., Keller, Lanea M. M., Albert, Paul S., Brechbiel, Martin W., Milenic, Diane E.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250925/
https://ncbi.nlm.nih.gov/pubmed/22229017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph5010001
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