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NMR Solution Structure of Rat Aβ(1–16): Toward Understanding the Mechanism of Rats' Resistance to Alzheimer's Disease

In an attempt to reveal the mechanism of rats' resistance to Alzheimer's disease, we determined the structure of the metal-binding domain 1–16 of rat β-amyloid (rat Aβ(1–16)) in solution in the absence and presence of zinc ions. A zinc-induced dimerization of the domain was detected. The z...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Istrate, Andrey N., Tsvetkov, Philipp O., Mantsyzov, Alexey B., Kulikova, Alexandra A., Kozin, Sergey A., Makarov, Alexander A., Polshakov, Vladimir I.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Biophysical Society 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250693/
https://ncbi.nlm.nih.gov/pubmed/22225807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.11.4006
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