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Blood Clot Formation under Flow: The Importance of Factor XI Depends Strongly on Platelet Count
A previously validated mathematical model of intravascular platelet deposition and tissue factor (TF)-initiated coagulation under flow is extended and used to assess the influence on thrombin production of the activation of factor XI (fXI) by thrombin and of the activation of factor IX (fIX) by fXIa...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250692/ https://ncbi.nlm.nih.gov/pubmed/22225793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.10.048 |
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