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Blood Clot Formation under Flow: The Importance of Factor XI Depends Strongly on Platelet Count

A previously validated mathematical model of intravascular platelet deposition and tissue factor (TF)-initiated coagulation under flow is extended and used to assess the influence on thrombin production of the activation of factor XI (fXI) by thrombin and of the activation of factor IX (fIX) by fXIa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fogelson, Aaron L., Hussain, Yasmeen H., Leiderman, Karin
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250692/
https://ncbi.nlm.nih.gov/pubmed/22225793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.10.048
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