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Blood Clot Formation under Flow: The Importance of Factor XI Depends Strongly on Platelet Count

A previously validated mathematical model of intravascular platelet deposition and tissue factor (TF)-initiated coagulation under flow is extended and used to assess the influence on thrombin production of the activation of factor XI (fXI) by thrombin and of the activation of factor IX (fIX) by fXIa...

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Autores principales: Fogelson, Aaron L., Hussain, Yasmeen H., Leiderman, Karin
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250692/
https://ncbi.nlm.nih.gov/pubmed/22225793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.10.048
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