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Myasthenogenicity of the main immunogenic region and endogenous muscle nicotinic acetylcholine receptors

In myasthenia gravis (MG) and experimental autoimmune MG (EAMG) many pathologically significant autoantibodies are directed at the main immunogenic region (MIR), a conformation-dependent region at the extracellular tip of α1 subunits of muscle nicotinic acetylcholine receptors (AChRs). Human muscle...

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Detalhes bibliográficos
Main Authors: LUO, JIE, LINDSTROM, JON
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250566/
https://ncbi.nlm.nih.gov/pubmed/21950318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08916934.2011.622015
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