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Myasthenogenicity of the main immunogenic region and endogenous muscle nicotinic acetylcholine receptors

In myasthenia gravis (MG) and experimental autoimmune MG (EAMG) many pathologically significant autoantibodies are directed at the main immunogenic region (MIR), a conformation-dependent region at the extracellular tip of α1 subunits of muscle nicotinic acetylcholine receptors (AChRs). Human muscle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LUO, JIE, LINDSTROM, JON
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250566/
https://ncbi.nlm.nih.gov/pubmed/21950318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08916934.2011.622015
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