Alternative Splicing of RNA Triplets Is Often Regulated and Accelerates Proteome Evolution

Thousands of human genes contain introns ending in NAGNAG (N any nucleotide), where both NAGs can function as 3′ splice sites, yielding isoforms that differ by inclusion/exclusion of three bases. However, few models exist for how such splicing might be regulated, and some studies have concluded that...

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Bibliographic Details
Main Authors: Bradley, Robert K., Merkin, Jason, Lambert, Nicole J., Burge, Christopher B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250501/
https://ncbi.nlm.nih.gov/pubmed/22235189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001229
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