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High MafB expression following burn augments monocyte commitment and inhibits DC differentiation in hemopoietic progenitors

We have previously shown that perturbed bone marrow progenitor development promotes hyporesponsive monocytes following experimental burn sepsis. Clinical and experimental sepsis is associated with monocyte deactivation and depletion of mDCs. Decrease in circulating DCs is reported in burn patients w...

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Détails bibliographiques
Auteurs principaux: Howell, Kirstin, Posluszny, Joseph, He, Li K., Szilagyi, Andrea, Halerz, John, Gamelli, Richard L., Shankar, Ravi, Muthu, Kuzhali
Format: Artigo
Langue:Inglês
Publié: Society for Leukocyte Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250307/
https://ncbi.nlm.nih.gov/pubmed/21984745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0711338
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