High MafB expression following burn augments monocyte commitment and inhibits DC differentiation in hemopoietic progenitors

We have previously shown that perturbed bone marrow progenitor development promotes hyporesponsive monocytes following experimental burn sepsis. Clinical and experimental sepsis is associated with monocyte deactivation and depletion of mDCs. Decrease in circulating DCs is reported in burn patients w...

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Autores principales: Howell, Kirstin, Posluszny, Joseph, He, Li K., Szilagyi, Andrea, Halerz, John, Gamelli, Richard L., Shankar, Ravi, Muthu, Kuzhali
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Leukocyte Biology 2012
Materias:
Cell Development, Differentiation, & Trafficking
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250307/
https://ncbi.nlm.nih.gov/pubmed/21984745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0711338
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