Bone marrow expression of poly(ADP-ribose) polymerase underlies diabetic neuropathy via hematopoietic-neuronal cell fusion

Diabetic neuropathy is the most common diabetic complication. The pathogenetic pathways include oxidative stress, advanced glycation end product (AGE) formation, protein kinase C, and NF-κB activation, as well as increased polyol flux. These metabolic perturbations affect neurons, Schwann cells, and...

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Bibliographic Details
Main Authors: Terashima, Tomoya, Kojima, Hideto, Chan, Lawrence
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2012
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250244/
https://ncbi.nlm.nih.gov/pubmed/21978940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-186262
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