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Palmitoylation influences the function and pharmacology of sodium channels
Palmitoylation is a common lipid modification known to regulate the functional properties of various proteins and is a vital step in the biosynthesis of voltage-activated sodium (Nav) channels. We discovered a mutation in an intracellular loop of rNav1.2a (G1079C), which results in a higher apparent...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250191/ https://ncbi.nlm.nih.gov/pubmed/22123950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108497108 |
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