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Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve

Endothelial-mesenchymal transformation (EMT) is a critical event for the embryonic morphogenesis of cardiac valves. Inducers of EMT during valvulogenesis include VEGF, TGF-β1, and wnt/β-catenin (where wnt refers to the wingless-type mammary tumor virus integration site family of proteins), that are...

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Detalhes bibliográficos
Main Authors: Balachandran, Kartik, Alford, Patrick W., Wylie-Sears, Jill, Goss, Josue A., Grosberg, Anna, Bischoff, Joyce, Aikawa, Elena, Levine, Robert A., Parker, Kevin Kit
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250145/
https://ncbi.nlm.nih.gov/pubmed/22123981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106954108
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