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Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age

In the human hematopoietic system, aging is associated with decreased bone marrow cellularity, decreased adaptive immune system function, and increased incidence of anemia and other hematological disorders and malignancies. Recent studies in mice suggest that changes within the hematopoietic stem ce...

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Detalhes bibliográficos
Main Authors: Pang, Wendy W., Price, Elizabeth A., Sahoo, Debashis, Beerman, Isabel, Maloney, William J., Rossi, Derrick J., Schrier, Stanley L., Weissman, Irving L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250139/
https://ncbi.nlm.nih.gov/pubmed/22123971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116110108
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