Therapeutic Implications for Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Neuropsychiatric Disorders

Striatal-enriched protein tyrosine phosphatase (STEP) is a brain-specific phosphatase that modulates key signaling molecules involved in synaptic plasticity and neuronal function. Targets include extracellular-regulated kinase 1 and 2 (ERK1/2), stress-activated protein kinase p38 (p38), the Src fami...

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Autori principali: Goebel-Goody, Susan M., Baum, Matthew, Paspalas, Constantinos D., Fernandez, Stephanie M., Carty, Niki C., Kurup, Pradeep, Lombroso, Paul J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2012
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Review Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250079/
https://ncbi.nlm.nih.gov/pubmed/22090472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.110.003053
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