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Deletion of Tuberous Sclerosis 1 in Somatic Cells of the Murine Reproductive Tract Causes Female Infertility

Tumors develop with dysregulated activation of mammalian target of rapamycin (mTOR), the kinase activity of which is kept in an inactive state by a tumor suppressor dimer containing tuberous sclerosis 1 (TSC1) and TSC2. We examined whether conditional deletion of TSC1 by a knock-in allele of the ant...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tanaka, Yoshihiro, Park, Joo Hyun, Tanwar, Pradeep S., Kaneko-Tarui, Tomoko, Mittal, Shilpi, Lee, Ho-Joon, Teixeira, Jose M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Endocrine Society 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249683/
https://ncbi.nlm.nih.gov/pubmed/22128018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1191
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