TGF-β Mediates Suppression of Adipogenesis by Estradiol through Connective Tissue Growth Factor Induction

In the bone marrow cavity, adipocyte numbers increase, whereas osteoblast progenitor numbers decrease with aging. Because adipocytes and osteoblasts share a common progenitor, it is possible that this shift is due to an increase in adipocyte-lineage cells at the expense of osteoblast-lineage commitm...

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Main Authors: Kumar, Ashok, Ruan, Ming, Clifton, Kari, Syed, Farhan, Khosla, Sundeep, Oursler, Merry Jo
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2012
Teme:
Growth Factors-Cytokines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249674/
https://ncbi.nlm.nih.gov/pubmed/22067314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1169
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