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Simvastatin inhibits osteoclast differentiation by scavenging reactive oxygen species

Osteoclasts, together with osteoblasts, control the amount of bone tissue and regulate bone remodeling. Osteoclast differentiation is an important factor related to the pathogenesis of bone-loss related diseases. Reactive oxygen species (ROS) acts as a signal mediator in osteoclast differentiation....

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Bibliografiske detaljer
Main Authors: Moon, Ho-Jin, Kim, Sung Eun, Yun, Young Pil, Hwang, Yu-Shik, Bang, Jae Beum, Park, Jae-Hong, Kwon, Il Keun
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society for Biochemistry and Molecular Biology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249586/
https://ncbi.nlm.nih.gov/pubmed/21832867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2011.43.11.067
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