Simvastatin inhibits osteoclast differentiation by scavenging reactive oxygen species

Osteoclasts, together with osteoblasts, control the amount of bone tissue and regulate bone remodeling. Osteoclast differentiation is an important factor related to the pathogenesis of bone-loss related diseases. Reactive oxygen species (ROS) acts as a signal mediator in osteoclast differentiation....

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Autori principali: Moon, Ho-Jin, Kim, Sung Eun, Yun, Young Pil, Hwang, Yu-Shik, Bang, Jae Beum, Park, Jae-Hong, Kwon, Il Keun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Biochemistry and Molecular Biology 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249586/
https://ncbi.nlm.nih.gov/pubmed/21832867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2011.43.11.067
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