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Productive association between MHC class I and tapasin requires the tapasin transmembrane/cytosolic region and the tapasin C-terminal Ig-like domain

The current model of antigen assembly with major histocompatibility complex (MHC) class I molecules posits that interactions between the tapasin N-terminal immunoglobulin (Ig)-like domain and the MHC class I peptide-binding groove permit tapasin to regulate antigen selection. Much less is known rega...

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Bibliografski detalji
Glavni autori: Simone, Laura C., Georgesen, Corey J., Simone, Peter D., Wang, Xiaojian, Solheim, Joyce C.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249531/
https://ncbi.nlm.nih.gov/pubmed/22169163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2011.11.002
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