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Effect of a tapasin mutant on the assembly of the mouse MHC class I molecule H2-K(d)

Major histocompatibility complex (MHC) class I heavy chain/β(2)m heterodimers assemble with antigenic peptides via interactions with peptide-loading complex proteins, including tapasin and ERp57. In human cells, a cysteine residue within tapasin (C95) has been shown to form a covalent bond with ERp5...

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Autores principales: Simone, Laura C, Wang, Xiaojian, Tuli, Amit, Solheim, Joyce C
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803334/
https://ncbi.nlm.nih.gov/pubmed/19687800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2009.59
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