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The mechanism of dynein motility: insight from crystal structures of the motor domain

Dynein is a large cytoskeletal motor protein that belongs to the AAA+ (ATPases associated with diverse cellular activities) superfamily. While dynein has had a rich history of cellular research, its molecular mechanism of motility remains poorly understood. Here we describe recent x-ray crystallogra...

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Autori principali: Cho, Carol, Vale, Ronald D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249483/
https://ncbi.nlm.nih.gov/pubmed/22062687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2011.10.009
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