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Transglutaminase 2 is a Marker of Chondrocyte Hypertrophy and Osteoarthritis Severity in the Hartley Guinea Pig Model of Knee OA

OBJECTIVE: The transglutaminase (TG) isoenzyme TG2, which catalyzes protein cross-linking via transamidation, influences healing phenotype in multiple forms of tissue injury. Moreover, TG2 knockout suppresses cartilage destruction but promotes osteophyte formation in instability-induced mouse knee O...

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Bibliografiske detaljer
Main Authors: Huebner, Janet L, Johnson, Kristen A., Kraus, Virginia B., Terkeltaub, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249463/
https://ncbi.nlm.nih.gov/pubmed/19328881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2009.02.015
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