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Collagen Fibril Disruption Occurs Early in Primary Guinea Pig Knee Osteoarthritis
OBJECTIVE: A major barrier inhibiting the discovery of structural modifying agents for osteoarthritis (OA) is an incomplete understanding of early disease events. Herein, we investigated the time course of collagen II cleavage and fibril disruption in the well-validated Hartley guinea pig model of s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826602/ https://ncbi.nlm.nih.gov/pubmed/19825496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2009.09.011 |
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