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Phorbol 12,13-Dibutyrate-Induced, Protein Kinase C-Mediated Contraction of Rabbit Bladder Smooth Muscle

Contraction of bladder smooth muscle is predominantly initiated by M(3) muscarinic receptor-mediated activation of the G(q/11)-phospholipase C β-protein kinase C (PKC) and the G(12/13)-RhoGEF-Rho kinase (ROCK) pathways. However, these pathways and their downstream effectors are not well understood i...

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Autors principals: Wang, Tanchun, Kendig, Derek M., Trappanese, Danielle M., Smolock, Elaine M., Moreland, Robert S.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249380/
https://ncbi.nlm.nih.gov/pubmed/22232602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2011.00083
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