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Estimation of Quantitative Trait Locus Effects with Epistasis by Variational Bayes Algorithms

Bayesian hierarchical shrinkage methods have been widely used for quantitative trait locus mapping. From the computational perspective, the application of the Markov chain Monte Carlo (MCMC) method is not optimal for high-dimensional problems such as the ones arising in epistatic analysis. Maximum a...

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Hlavní autoři: Li, Zitong, Sillanpää, Mikko J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249367/
https://ncbi.nlm.nih.gov/pubmed/22042575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.134866
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