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Insight into Molecular Basis of Curing of [PSI(+)] Prion by Overexpression of 104-kDa Heat Shock Protein (Hsp104)

Yeast prions are a powerful model for understanding the dynamics of protein aggregation associated with a number of human neurodegenerative disorders. The AAA+ protein disaggregase Hsp104 can sever the amyloid fibrils produced by yeast prions. This action results in the propagation of “seeds” that a...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Helsen, Christopher W., Glover, John R.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249108/
https://ncbi.nlm.nih.gov/pubmed/22081611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.302869
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