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Multiple SecA Molecules Drive Protein Translocation across a Single Translocon with SecG Inversion
SecA is a translocation ATPase that drives protein translocation. D209N SecA, a dominant-negative mutant, binds ATP but is unable to hydrolyze it. This mutant was inactive to proOmpA translocation. However, it generated a translocation intermediate of 18 kDa. Further addition of wild-type SecA cause...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249098/ https://ncbi.nlm.nih.gov/pubmed/22074917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.301754 |
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