Unifying Concept of Serotonin Transporter-associated Currents

Serotonin (5-HT) uptake by the human serotonin transporter (hSERT) is driven by ion gradients. The stoichiometry of transported 5-HT and ions is predicted to result in electroneutral charge movement. However, hSERT mediates a current when challenged with 5-HT. This discrepancy can be accounted for b...

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Autori principali: Schicker, Klaus, Uzelac, Zeljko, Gesmonde, Joan, Bulling, Simon, Stockner, Thomas, Freissmuth, Michael, Boehm, Stefan, Rudnick, Gary, Sitte, Harald H., Sandtner, Walter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Molecular Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249096/
https://ncbi.nlm.nih.gov/pubmed/22072712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.304261
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