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Novel bioactive metabolites of dipyrone (metamizol)

Dipyrone is a common antipyretic drug and the most popular non-opioid analgesic in many countries. In spite of its long and widespread use, molecular details of its fate in the body are not fully known. We administered dipyrone orally to mice. Two unknown metabolites were found, viz. the arachidonoy...

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Bibliografische gegevens
Hoofdauteurs: Rogosch, Tobias, Sinning, Christian, Podlewski, Agnes, Watzer, Bernhard, Schlosburg, Joel, Lichtman, Aron H., Cascio, Maria G., Bisogno, Tiziana, Di Marzo, Vincenzo, Nüsing, Rolf, Imming, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248997/
https://ncbi.nlm.nih.gov/pubmed/22172309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.11.028
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