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Novel bioactive metabolites of dipyrone (metamizol)

Dipyrone is a common antipyretic drug and the most popular non-opioid analgesic in many countries. In spite of its long and widespread use, molecular details of its fate in the body are not fully known. We administered dipyrone orally to mice. Two unknown metabolites were found, viz. the arachidonoy...

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Hlavní autoři: Rogosch, Tobias, Sinning, Christian, Podlewski, Agnes, Watzer, Bernhard, Schlosburg, Joel, Lichtman, Aron H., Cascio, Maria G., Bisogno, Tiziana, Di Marzo, Vincenzo, Nüsing, Rolf, Imming, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248997/
https://ncbi.nlm.nih.gov/pubmed/22172309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.11.028
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