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Novel bioactive metabolites of dipyrone (metamizol)

Dipyrone is a common antipyretic drug and the most popular non-opioid analgesic in many countries. In spite of its long and widespread use, molecular details of its fate in the body are not fully known. We administered dipyrone orally to mice. Two unknown metabolites were found, viz. the arachidonoy...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Rogosch, Tobias, Sinning, Christian, Podlewski, Agnes, Watzer, Bernhard, Schlosburg, Joel, Lichtman, Aron H., Cascio, Maria G., Bisogno, Tiziana, Di Marzo, Vincenzo, Nüsing, Rolf, Imming, Peter
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248997/
https://ncbi.nlm.nih.gov/pubmed/22172309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.11.028
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