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Novel bioactive metabolites of dipyrone (metamizol)

Dipyrone is a common antipyretic drug and the most popular non-opioid analgesic in many countries. In spite of its long and widespread use, molecular details of its fate in the body are not fully known. We administered dipyrone orally to mice. Two unknown metabolites were found, viz. the arachidonoy...

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Detalhes bibliográficos
Main Authors: Rogosch, Tobias, Sinning, Christian, Podlewski, Agnes, Watzer, Bernhard, Schlosburg, Joel, Lichtman, Aron H., Cascio, Maria G., Bisogno, Tiziana, Di Marzo, Vincenzo, Nüsing, Rolf, Imming, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248997/
https://ncbi.nlm.nih.gov/pubmed/22172309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.11.028
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