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Replacement of Mycobacterium smegmatis dnaA gene by M. tuberculosis homolog results in temperature sensitivity

The genetic aspects of DnaA mediated initiation of oriC replication in mycobacteria are largely unknown. To get insights into the replication initiation process in mycobacteria, we characterized Mycobacterium tuberculosis DnaA and its interactions with oriC. We show that the replacement of M. smegma...

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Bibliographische Detailangaben
Hauptverfasser: Madiraju, Murty, Madiraju, Sai Chandanda, Yamamoto, Kohji, Greendyke, Rebecca, Rajagopalan, Malini
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248996/
https://ncbi.nlm.nih.gov/pubmed/22112933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2011.10.023
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