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Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction
Bioassay-guided fractionation of two cyanobacterial extracts from Papua New Guinea has yielded hoiamide D in both its carboxylic acid and conjugate base forms. Hoiamide D is a polyketide synthase (PKS)/non-ribosomal peptide synthetase (NRPS)-derived natural product that features two consecutive thia...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248991/ https://ncbi.nlm.nih.gov/pubmed/22104152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.10.054 |
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