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Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction

Bioassay-guided fractionation of two cyanobacterial extracts from Papua New Guinea has yielded hoiamide D in both its carboxylic acid and conjugate base forms. Hoiamide D is a polyketide synthase (PKS)/non-ribosomal peptide synthetase (NRPS)-derived natural product that features two consecutive thia...

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Sonraí Bibleagrafaíochta
Main Authors: Malloy, Karla L., Choi, Hyukjae, Fiorilla, Catherine, Valeriote, Fred A., Matainaho, Teatulohi, Gerwick, William H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248991/
https://ncbi.nlm.nih.gov/pubmed/22104152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.10.054
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